Lt.-Gov. John Graves Simcoe chooses a 380-acre site on Penetanguishene Harbour for a naval and military base to protect the Upper Great Lakes from American threats following the War of 1812.

The military site is decommissioned and turned over to the Government of Upper Canada.

Boys Reformatory of Upper Canada is established in the abandoned barracks.

Barracks are consumed in a fire, leading to the construction of a new building higher up the hill.

Reformatory residents are moved to other provincial institutions or community placements, and the building is converted into a facility for individuals suffering from mental health problems.

Four wards are added to Oak Ridge, bringing the patient capacity to 300.

Brébeuf and Bayfield buildings are opened. The identical buildings were designed as apartment-style living quarters to simulate life in the community.

The name of the institution is changed to the Mental Health Centre, and work begins on the Toanche Building.

Construction of the Oak Ridge Activity Centre, with a new pool and gym, is completed.

The Ontario Government includes funding to replace the aging Oak Ridge building in its budget.

Waypoint is divested from the Ministry of Health and Long-Term Care and is now a public hospital corporation sponsored by the Catholic Health Sponsors of Ontario.

As part of a rebranding process, the hospital changes its name to Waypoint Centre for Mental Health Care.

The purpose-built, state-of-the-art Atrium building opens its doors to patients from Oak Ridge and Brébeuf.